Hemostatic Studies Sudanese Patients with Sickle ceel anemia

Abstract

Sickle cell anemia is a common disease in Sudan. Homozygous patients suffer from hemolytic anemia and other serious complications. The underlying pathology of much of these complications is the occurrence of vasoocclusion due to micro thrombi formation resulting in organ ischemia. Activation of coagulation system as well as increased fibrinolysis have been reported in SCA. This is the first study in Sudan in which hemostatic derangements in patients with sickle cell anemia are examined.