The Histology of the Submandibular Gland in the Sudanese
The Histology of the Submandibular Gland in the Sudanese
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Date
2015-04-12
Authors
Mahmoud,Hagir A. Rahman
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Journal ISSN
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Publisher
UOFK
Abstract
Introduction: The submandibular gland is a mixed salivary gland that
contributes the majority of saliva secreted into the mouth. Sudan is a hot
tropical country. As an adaptive response to this hot environment, it is
assumed that this gland in the Sudanese could be entirely serous or has little
mucous cells compared to other nations.
Objective: To study the normal submandibular gland histology in the
Sudanese people, and to compare it with that of other nations.
Material and methods: twenty normal submandibular salivary glands were
obtained as a part of radical neck dissection performed at Khartoum
Teaching Dental Hospital. The morphology of the submandibular gland was
studied using macroscopic and microscopic techniques. The gland volume
was obtained by using the water displacement technique. The length, width,
and thickness of the gland were measured. For histological analysis, the
sections were fixed in formalin and embedded in paraffin for routine
processing. Ten Serial sections were stained with hematoxylin & eosin stain.
A simple point-counting method was used and the volume fractions of
various constituents of individual glands were determined.
V
Results: The results showed that the average submandibular gland measures
were 4.1 cm in length, 3.1 cm in width, 1.1 cm in thickness, and 15.9 cm3 in
volume. The mean of the proportional volume of total acinar cells from total
points of the gland was 56%. That of the duct was 9.52%, and the mean of
the proportional volume of stroma from total glandular points was 34.5%.
The mean of the proportional volume of the serous acini from the total
acinar cells was 97.5%, and that of the mucous acini was 2.5%. There were
no differences in the distribution of serous and mucous acini between the
central and peripheral sections.
Conclusion: It is concluded that in the Sudanese, the volume of the serous
acinar cell constitute 97.5% of the total acinar cell volume which is much
higher than the 92,2% volume reported by Scott from England. The study
provides an average of normal gland dimensions which is important to
ensure the proper diagnosis of salivary gland diseases. The differences in
volumes between this and other studies could be an adaptive form of
hypertrophy of the gland to compensate for the hot environment.
Description
Keywords
Histology, Submandibular, Gland,