Haemovigilance: post-transfusion malaria as an example

Abstract

Blood transfusion is beneficial and life saving measure in many cases, but some times carries some risks for recipients, so measures should be taken to prevent or minimize these blood transfusion associated risks(Haemovigilance), along the blood transfusion chain in blood bank and hospital by collecting information and analysis of collected data for assessment and evaluation. This study is directed to determine the prevalence of P. falciparum infection and anti MSP1-19 among clinically healthy blood donors as an example for haemovigilance system, and to initiate a haemovigilance system to improve blood transfusion safety and efficacy, for the first time in Sudan in police hospital blood bank. Beside examination that concern safety of blood transfusion which include HIV and HBV, screening for P. falciparum malaria has been included in this study. And we found that 1.2% of the blood donors were HIV seropositive, 8.6% were HBV seropositive, 9% were microscopically positive for P. falciparum malaria (ring stage), and 11.1% were ICT positive, and 32.95% were immunoglobulin positive for MSP1-19 In pre- transfusion screening of recipients for P. falciparum malaria we found that 0.8% were microscopically positive, 4.8% were ICT positive and 12.3% were immunoglobulin positive for MSP1-19 In post transfusion screening of recipients for P. falciparum malaria we found that 14.6% were microscopically positive, 14.4% were ICT positive and 14.8% were immunoglobulin positive for MSP1-19.