Anti-plasmodial Effects of Azadirachta indica (Neem-Leaves) in Experimental Cerebral Malaria: Apoptosis of Cerebellar Purkinje Cells of Mice as a Marker.

Abstract

Malaria is a major public health problem in the world, treatment of malaria is becoming more difficult due to increasing drug resistance. Therefore, the need for alternative drugs is acute. Pharmaceutical research in natural products represents a major strategy for discovering and developing new drugs. The use of medicinal plants for the treatment of parasitic diseases is well documented since ancient times e.g. the use of Azadirachta indica (Neem) as an anti-malarial.