Aetiology of Proximal Weakness among Adult Sudanese patients

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Date
2008-03
Authors
Hussein, Abbashar
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Publisher
University of Khartoum
Abstract
Objective: To determine the aetiology of proximal myopathy among adult Sudanese patients seen in Elshaab Teaching Hospital. Methods: This is a descriptive cross sectional hospital based study conducted in Elshaab Teaching Hospital, during the period from January 2004 – September 2005. 100 adult Sudanese patients with proximal myopathy were reviewed, detailed history and proper clinical examination was done by the authors. Results: The most frequent cause of proximal myopathy was found to be muscular dystrophy whic accounted for 30% of the cases, followed by myasthenia gravis 20%, polymyositis and dermatomyositis 14%, Guillain Barre 8%, diabetes mellitus 5%, connective tissue diseases 5%, thyrotoxicosis 3%, chronic renal failure 3%, malignancy 2%, drugs (steroids and chloroquine) 2%, alcohol 2%. Spinal muscular atrophy, hypokalaemia, and hypocalcaemia each accounted for 1%. Conclusion: The study showed that the incidence of proximal myopathy is more common among females. Proximal muscle weakness involved the lower limbs more than the upper limbs.
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Keywords
myopathy, Guillain Barre, dermatomyositis, polymyositis, hypokalaemia, atrophy
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