PATTERN OF BACRERIAL INFECTION IN UNDER TWO MONTH INFANTS IN MYGOMA HOME FOR ORPHANGE KHARTOUM – SUDAN
PATTERN OF BACRERIAL INFECTION IN UNDER TWO MONTH INFANTS IN MYGOMA HOME FOR ORPHANGE KHARTOUM – SUDAN
No Thumbnail Available
Date
2015-04-08
Authors
Sayed, Nazra
Journal Title
Journal ISSN
Volume Title
Publisher
UOFK
Abstract
Neonatal sepsis is a life threatening emergency and any
delay in diagnosis and treatment may result in death.
The objectives of this study were to a) determine the
causative bacterial pathogen in under two months orphanage
children, who are admitted to Mygoma Home either (i)for less
than72hoursor (ii)more than 72 hours, and to study the
antimicrobial sensitivity, b) to study clinical presentation and c)
study the short term outcome (2 weeks) of neonatal sepsis.
The study was a prospective institution-based study,
carried out in Mygoma Home for children, on daily bases from
October 2004 to December 2004. Sepsis screening was done on
150 infants with signs and symptoms of neonatal sepsis, Blood,
urine, Umbilical swabs and CSF culture had been taken.
The most frequent causative organisms for infants in
whom sepsis assessment was done within 72 hours of admission,
were coagulase -ve staphylococcus in 17 (40%) infants. E. coli in 6
(14.2%) infants, Klebsiella in 6 (14.2%) infants, and Staph. aureus
in 6 (14.2%) infants.
On the other hand organisms isolated from infants
admitted for more than 72 hrs were coagulase negative
V
staphylococcus in15 (38.4%)infants, followed by E. coli in 9 (23%)
infants, Klebsiella in 5(12.8%) infants salmonella and staph aureus
in 3 (7.6%)infants, for each.
The commonest five organisms had low sensitivity to
ampicillin, except Klebsiella which had high sensitivity to it.
Coagulase negative staphylococci, salmonella, Klebsiella
had a high sensitivity to gentamicin, while E. coli and Staph.
aureus had low sensitivity to it.
E. coli, Klebsiella and Staph. aureus had a high sensitivity
to cloxacillin, while coagulase negative staphylococcus and
Salmonella had low sensitivity to it.
The mortality rate of the neonatal sepsis in this study was 8%.
It is essential for every Neonatal Unit to monitor, its rate of
infection and the organisms commonly encountered, as well as its
sensitivity and resistance to the commonly used antibiotics, and
several steps to control infections must be adopted.
Description
137page
Keywords
Neonatal sepsis,BACRERIAL INFECTION,MYGOMA HOME,ORPHANGE KHARTOUM