Analysis of Glutathione Transferases Mu1 and Theta1 in Sudanese patients with Leukaemia

Abstract

Glutathione S-transferases are a family of phase II detoxifying enzymes that catalyze the nucleophilic attack of Glutathione to a wide variety of endogenous and exogenous electrophilic compounds such as products of oxidative stress and environmental pollutants. These compounds play an important role in maintaining DNA integrity.