Comparative Efficacy and Economic Impact of Some Commonly Used Antibiotics and Anthelmentic Drugs in the Veterinary Field in the Sudan

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Date
2015-06-23
Authors
Khadiga Mohamed Osman Abdalla, Abdalla
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Publisher
UOFK
Abstract
Efficacy of doramectin subcutaneously administered at its recommended therapeutic dose of 0.2 mg/kg body weight against sarcoptic mange mites in goats was evaluated and it was found that the drug was 100% efficacious in eliminating mange mites and gave protection for up to 6 weeks from reinfection. The protective efficacy of doramectin also against experimental infestation by Hyalomma anatolicum anatolicum was studied by injecting subcutaneously the drug at a dose rate of 1 mg/kg in rabbits, 2 days and 4 days before infestation. There was a significant decrease in weights of engorged female ticks and in the weight of egg batches, with decreased per cent hatchability by 19.83% on day 4 post-injection. The two groups showed significant prolongation of feeding and pre-oviposition periods, and decreased oviposition periods. In the two groups the estimated reproductive factor was significantly reduced and per cent inhibition of oviposition was 15.5% on day 2 post-injection and 90.8% on day 4 post-injection. Toxic actions of doramectin intravenously administered at doses of 0.2 mg/kg and 0.6 mg/kg body weight in goats on biochemical and haematological parameters was studied and the drug proved to be safe both at its recommended therapeutic dose and 3 times that dose, and there was a significant increase in the number of white blood cells after injection of the drug
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Comparative Efficacy and Economic Impact of Some Commonly Used Antibiotics and Anthelmentic Drugs in
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