Anticestodal Activity of Some Sudanese Medicinal Plants in Avians

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Isharaga Sayed Abdel Hafiz, Hafiz
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University of Khartoum
An investigation is described in which Bovan chicks were infected with Raillietina tetragona at 5 cysticercoids/chicks. 21- days post infection, effectiveness of Albizia anthelmintica methanol extract single doses of 5, 3, 2 and 1.5 gm/kg body weight or repeated doses of 1.5 gm/kg body weight for 2 successive days, V. amygdalina methanol extract repeated doses of 5, 10, 15 and 25 gm/kg body weight for 3 successive days, praziquantel 50 mg/ kg body weight and tapinex 150 mg/kg body weight against the tapeworms were estimated. Effectiveness of A. anthelmintica methanol extract was 100% at single doses of 3, 2 and 20 %, 50% at 1.5 gm/kg body weight and 1.5 gm / kg body weight repeated doses, respectively. A. anthelmintica methanol extract at 5 gm/kg body weight was lethal to the chicks and the lethality decreased at 3 gm/kg body weight with 100 % efficacy whereas at 2, 1.5 single dose or 1.5 gm/kg body weight repeated doses no deaths occurred. Effectiveness of V. amygdalina methanol extract ranged from 20% (at 5 gm/kg body weight) to 36.66 % (at 25 gm / kg body weight) but was not toxic to the chicks. Praziquantel 50 mg/kg body weight and tapinex 150 mg/kg body weight resulted in 100% and 36.66% efficacy, respectively. Raillietina tetragona infection in chicks caused enteritis, lymphocytic infiltration in the lamina propria of the intestines and erosions on the intestinal epithelium. In some instance, the infection was associated with hepatic changes and lymphocytic infiltration. Congestion of the hepatic and kidney blood vessels was correlated with changes in serum constituents.
Anticestodal Activity of Some Sudanese Medicinal Plants in Avians