Investigations of renal functions of hypo and hyperthyroid Sudanese females

Abstract

The present study has been designed and conducted to investigate the effect of thyroid diseases on renal function by estimation of the levels of serum urea,creatinine, uric acid , calcium, sodium, potassium and phosphorus concentrations. The subjects included in this study were 59 thyroid dysfunction patients (hyper and hypothyroidism) before and after treatment. They divided into two groups: Group (A): untreated patients (hyper and hypothyroidism). Group (B): under treatment (hyper and hypothyroidism). All of them were females attended in radiation and isotopes center Khartoum and other 15 healthy Sudanese females (group C) were taken as a control group. Serum samples were analyzed using radioimmunoassay and spectrophotometer methods, the mean of serum concentration levels of urea showed clear increased in all patients before and after treatment but the means of serum concentration levels of creatinine and uric acid showed no differences compared to the euthyroid subjects. Also there was simple increased on serum concentrations of calcium, potassium and phosphorus levels in hyperthyroidism compared to the euthyroid subjects. The present study showed that there is no direct effect of thyroid disease on renal function of Sudanesefemales with thyroid dysfunction