Sequence Analysis and Phylogenetic Relationship of Echinococcus granulosus Isolates recovered from the one Humped Camel (Camelus dromedaries) in Central Sudan

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حسن, كمال الدين
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University of Khartoum
Cystic echinococcosis (CE), caused by larval stage of Echinococcus granulosus (EG) complex, affects livestock and humans in the Sudan, hence the disease is of major public health importance. Currently, 10 distinct genotypes designated as (G1-G10) have been described worldwide, based on nucleotide sequence analysis of the mitochondrial cytochrome C oxidase subunit 1 (CO1) and NADH dehydrogenase 1 genes. These different genotypes have been associated with distinct, intermediate hosts: sheep, pigs, cattle, horses, camels, goats and cervids. Of the ten genotypes of EG, sheep strain (G1), cattle strain (G5) and camel strain (G6) are enzootic in the Sudan. In this study, the molecular characterization of 40 EG isolates from camels was performed by genetic study and phylogenetic analysis of a fragment of the mitochondrial NADH 1 gene to define the circulating genetic variants in a hyper endemic areas of Tmboul, Central Sudan.
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Sequence, Analysis , Phylogenetic ,Relationship