The Effect of Preoperative Oral Erythromycin on Residual Gastric Volume & Acidity

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Date
2015-04-01
Authors
Mukhtar, Nawal
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Publisher
UOFK
Abstract
A prospective study was done on 100 patients presented for elective surgery under general anaesthesia in Khartoum Teaching Hospital and Soba University Hospital during the period from March, 2001 to September, 2002. The study aimed to study the effect of 250 mg oral erythromycin on residual gastric volume and acidity. Patients were divided into 4 groups each consists of 25 patients:- Group A: Control group, group B: received erythromycin 1 hour prior to induction of anaesthesia, group C: received erythromycin 2 hours prior to induction of anaesthesia, group D: received erythromycin 3 hours prior to induction of anaesthesia. The study concluded that 250 mg oral erythromycin significantly reduced residual gastric volume when given 2 or 3 hours prior to induction of anaesthesia without significant changes in gastric pH. Also it did not significantly reduce residual gastric volume or acidity when given 1 hour prior to induction of anaesthesia.
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Keywords
Preoperative Oral, Erythromycin,Residual, Gastric Volume,Acidity
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