Molecular characterization of Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutations in isolates from eastern Sudan

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Date
2015-02
Authors
maha, dr.
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Publisher
UOFK
Abstract
In Sudan sulfadoxine-pyrimethamine (SP) was the second line antimalarial treatment for uncomplicated falciparum malaria till June 2004 when the first and second line antimalarial drugs have been switched to Artesunate plus SP and Artemether plus lumefanterene, respectively. Treatment failure caused by SP resistant P. falciparum has been reported in Khartoum, eastern and southern Sudan.
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Keywords
sulfadoxine-pyrimethamine (SP) ,falciparum, dihydrofolate, reductase,(dhfr) ,synthase
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