Pre and Post Renal Levels Of Some Enzymes In Hemo-Dialysis Of Patients With Chronic Renal Failure.

Abstract

This study was conducted to compare the concentration of plasma enzymes in chronic renal failure pre dialysis (group A) and post dialysis (group B), and evaluate the concentration of these enzymes between pre and post dialysis. The study was performed in 25 samples of Sudanese patients (chronic renal failure) and compared with 15 samples as the control groups. Plasma samples were analyzed using spectrophotometer methods, plasma concentration of these enzymes showed increased in chronic renal failure pre and post dialysis. The mean values of lactate dehydrogenase pre dialysis is 259IU/L, post dialysis is 276IU/L, the mean of creatine kinase pre dialysis is 252IU/L, and post dialysis is 241 IU/L but the mean of amylase pre and post dialysis is the same 144 IU/L. This study showed that there is no difference of concentration of amylase enzyme, but the difference concentration of CK and LDH between pre and post dialysis during chronic renal failure depend on normal range of this enzyme in control groups.