Activity test ofCommiphora myrrhto Helicobacter pylori compared with commonly used Antimicrobial Agents
Activity test ofCommiphora myrrhto Helicobacter pylori compared with commonly used Antimicrobial Agents
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Date
2015-04-07
Authors
Salih,Huda Mohamed El Mahdi
Journal Title
Journal ISSN
Volume Title
Publisher
University of Khartoum
Abstract
The present study aimed to isolate Helicobacter pyloriand conduct the susceptibility
tests to Commiphora myrrhin comparison with widely used antibiotics. The study
samples were collected from Sudanese patients who were suffering from peptic disease
during the period September 2006 to November 2007 in Ibn Sina T. Hospital.
The study population was 52 females and 48 males their ages ranged between 19 and 70
years. It was observed that high prevalence ofHelicobacter pylori infection in old ages .
The study included 32 manual worker, 31 house wives and 15 students , 6 farmers and
16 other jobs (Doctors ,Employers ,Engineers and Teachers). Helicobacter pyloriwas
isolated in sixty of the total of one hundred specimen collected. The sensitivity tests
were done against Amoxicillin, tetracycline ,Metronidazole and Clarithromycin by disk
diffusion method and Commiphora myrrh extraction by agar dilution in four dilution
1/20,1/40,1//80 and 1/160. Itwas found that 71% of isolates were sensitive to
Amoxicillin, 61.7%Tetracycline ,38.3% to Metronedazole and35% to Clarithromicin ,In
Commiphora myrrh dilution one (1/20)which highist sensitivity rate 100% . Dilution
two(1/40) 90% .50% for dilution three(1/80). And 20 % for dilution four (1/160) . That
means that Amoxicillin is the best choice and the MIC of Commiphora myrrh extraction
is 1/20 and Commiphora myrrh may be examined as an alternative treatment against
Helicobacter pylori
Description
88 Pages
Keywords
Antimicrobial Agents,Helicobacter,Commiphora myrrh,Abbreviations,Antimicrobial Agents,Activity test Commiphora