Y chromosome sequence variation and the history of human populations

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dc.FacultyEndemic Diseasesen_US
dc.contributor.authorIbrahim, Muntaser E.
dc.contributor.authorA. Underhill, Peter
dc.contributor.authorBertranpetit, Jaume
dc.contributor.editoren_US
dc.contributor.otherMolecular Biologyen_US
dc.date2000
dc.date.accessioned2015-11-12T08:13:37Z
dc.date.available2015-11-12T08:13:37Z
dc.date.issued2015-11-12
dc.date.submitted2015
dc.description.abstractBinary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic legacy of our species that has persisted to the present, permitting inference of human evolution, population affinity and demographic history1. We used denaturing highperformance liquid chromatography (DHPLC; ref. 2) to identify 160 of the 166 bi-allelic and 1 tri-allelic site that formed a parsimonious genealogy of 116 haplotypes, several of which display distinct population affinities based on the analysis of 1062 globally representative individuals. A minority of contemporary East Africans and Khoisan represent the descendants of the most ancestral patrilineages of anatomically modern humans that left Africa between 35,000 and 89,000 years ago.en_US
dc.identifier.urihttp://khartoumspace.uofk.edu/123456789/17011
dc.language.isoenen_US
dc.publisherUOFKen_US
dc.subjectY chromosome sequenceen_US
dc.subjectvariationen_US
dc.subjecthistoryen_US
dc.subjecthuman populationsen_US
dc.titleY chromosome sequence variation and the history of human populationsen_US
dc.typePublicationen_US

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