Primary Cutaneous Follicular Lymphoma Associated with Helicobacter pylori Infection

dc.FacultyEndemic Diseasesen_US
dc.contributor.authorIbrahim, Muntaser E.
dc.contributor.authorAlfarouk, Khalid Omer
dc.contributor.authorYousif, Sabah
dc.contributor.authoretal.
dc.contributor.otherMolecular Biologyen_US
dc.date2013-08
dc.date.accessioned2015-11-18T10:35:21Z
dc.date.available2015-11-18T10:35:21Z
dc.date.issued2015-11-18
dc.date.submitted2015
dc.description.abstractA 66 year o ld male with a long standing uncontrolled gastric H pylori infection and Crohn’s disease presented with nodular lesions in the back. These were removed surgically. Pathologically the lesion consisted of lymphocytes, giant cells with vacuolated cytoplasm and histiocytes. By immunohistochemistry there were stem cells, B cells and CD1a Langerhans cells. The diagnosis of Langerhans histiocytosis was made. The giant cells were positive for both CD 20 B cell marker and the macrophage marker CD 68 indicating that they were derived from B cells. They were strongly positive for H pylori antigen. A year later the patient reported with non-itching nodular lesions in the right flank. There was no lymphadenopathy or Splenomegaly. A biopsy of the lesion showed a follicular center B cell lymphoma. The tumor cells were positive for H pylori antigen. He was treated for H pylori infection. He completely recovered and was in good health a year later.en_US
dc.identifier.urihttp://khartoumspace.uofk.edu/123456789/17226
dc.language.isoenen_US
dc.publisherUOFKen_US
dc.subjectLangerhans Histiocytosis, H. pylori infection, Cutaneous Follicular B cell lymphomaen_US
dc.titlePrimary Cutaneous Follicular Lymphoma Associated with Helicobacter pylori Infectionen_US
dc.typePublicationen_US

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