Interplay between AMA1 immunisation and parasite challenge leads to protection against malaria infection in rhesus macaques

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dc.FacultyEndemic Diseasesen_US
dc.contributor.authorAbdel Hamid, Muzamil M.
dc.contributor.authorJ Remarque, Edmond
dc.contributor.authorFaber, Bart W
dc.contributor.editorAbdel Hamid, Muzamil M.en_US
dc.date2010
dc.date.accessioned2015-11-12T06:28:24Z
dc.date.available2015-11-12T06:28:24Z
dc.date.issued2015-11-12
dc.date.submitted2015
dc.description.abstractPlasmodium knowlesi (Pk), a simian malaria parasite, is a suitable primate model for Plasmodium falciparum (Pf), and it was recently identified as the fifth human malaria parasite [1]. To test the ability of yeast-expressed PkAMA1 (Figure 1) to protect rhesus macaques upon challenge with Pk, six healthy rhesus monkeys were vaccinated with PkAMA1 and six control monkeys were vaccinated with PfAMA1 formulated in an oil in water adjuvant [2]. All monkeys received three i.m. vaccinations at 4 week intervalsen_US
dc.identifier.urihttp://khartoumspace.uofk.edu/123456789/16992
dc.publisheruniversity of khartoumen_US
dc.subjectInterplay between AMA1 immunisation and parasite challenge leads to protection against malaria infection in rhesus macaquesen_US
dc.titleInterplay between AMA1 immunisation and parasite challenge leads to protection against malaria infection in rhesus macaquesen_US
dc.typePublicationen_US

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